Which is the drug of choice for cyanide poisoning?

Which is the drug of choice for cyanide poisoning?

Which is the drug of choice for cyanide poisoning?

Lorazepam is the drug of choice; midazolam and phenobarbital are second-line agents. Cyanide antidotes are the key medications for hydrogen cyanide (HCN) poisoning. Hydroxocobalamin (HCO, vitamin B-12) is the first-line therapy for cyanide toxicity.

How do paramedics treat cyanide poisoning?

Treatment of cyanide poisoning includes high-flow oxygen, inhaled amyl nitrite and a combination of intravenous sodium nitrite and sodium thiosulfate. An antidote kit containing intravenous hydroxocobalamin (Cyanokit) is also available.

Is oxygen an effective treatment for cyanide?

(Although theoretically useless, supportive care with administration of oxygen alone has proven effective in a number of poisonings.) It can also treat concomitant carbon monoxide exposure, pending measurement of blood levels. Administer cyanide antidotes as soon as possible.

Which antianginal drug is useful for emergency treatment of cyanide poisoning Mcq?

Amyl Nitrite is a prescription medicine used to treat the symptoms of Acute Relief of Angina, and Cyanide Poisoning.

What is in a cyanide antidote kit?

Each Cyanide Antidote Kit contains: 2 Ampules Sodium Nitrite Injection (300 mg in10mL of water) 2 Vials Sodium Thiosulfate Injection (12.5 g in 50mL of water) 12 Ampules Amyl Nitrite Inhalants (0.3 mL)

What is methylene blue an antidote for?


Does cyanide bind to hemoglobin?

After exposure to HCN, cyanide ion tightly binds with hemoglobin to produce cyanhemoglobin, which can cause severe hypoxia.

How do you use cyanide antidote kit?

Antidote Administration

  1. The starting dose of Cyanokit for adults is 5 g, (two 2.5 g vials) administered by IV infusion over 15 minutes.
  2. Depending upon the severity of the poisoning and the clinical response, a second dose of 5 g may be administered by IV infusion for a total dose of 10 g.

Can a doctor prescribe amyl nitrate?

Amyl nitrite is available only with your doctor’s prescription.

When is amyl nitrite used?

Amyl nitrite is related to the nitrate medicines and is used by inhalation to relieve the pain of angina attacks. It works by relaxing blood vessels and increasing the supply of blood and oxygen to the heart while reducing its workload.