What should I monitor for ezetimibe?

Posted on December 23, 2019
by Laura Bush
December 23, 2019
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Table of Contents

What should I monitor for ezetimibe?

Assessment

Monitor liver function tests prior to initiation of therapy and as clinically indicated.
If patient develops muscle tenderness during therapy, CPK levels should be monitored.
May cause ↑ in fasting serum glucose levels and in HbA1c.
May cause ↑ AST, ALT and creatine phophokinase.
May cause hyperkalemia.

How effective is Zetia in lowering LDL?

Zetia is a cholesterol absorption inhibitor. Zetia lowers cholesterol by reducing the amount of cholesterol that is absorbed from the small intestine. In a clinical study Zetia reduced cholesterol absorption from small intestine by 54%.

Does ezetimibe lower triglyceride levels?

Official Answer. Yes, ezetimibe does lower triglyceride levels. In an analysis of eight clinical trials comparing ezetimibe 10mg daily to a placebo, the patients on ezetimibe had a reduction in triglycerides of 8%.

Which drug has greatest effect on LDL cholesterol lowering?

Statin drugs lower LDL cholesterol by slowing down the liver’s production of cholesterol. They also increase the liver’s ability to remove LDL cholesterol that is already in the blood. The Food and Drug Administration (FDA) offers advice on the risks related to taking statins: Controlling Cholesterol with Statins.

How much does Zetia lower triglycerides?

Triglyceride levels were reduced by 14.0% when ezetimibe was added to ongoing statin monotherapy and by 2.9% when placebo was added (P < 0.001).

What is the indication of ezetimibe?

Pharmacology. Ezetimibe is indicated to reduce elevated total-C, LDL-C, Apo B, and non-HDL-C in patients with primary hyperlipidemia, alone or in combination with an HMG-CoA reductase inhibitor (statin).

Is a statin better than Zetia?

Official Answer. Whether Zetia is better or worse than a statin at reducing cholesterol depends on the individual patient. Zetia and statins reduce cholesterol each with their own different mode of action.

What is the difference between Zetia and ezetimibe?

Zetia is a brand-name drug that contains the active drug ezetimibe. This active drug is also available as a generic medication. A generic drug is an exact copy of the active drug in a brand-name medication. The generic is considered to be as safe and effective as the original drug.

How do I get my LDL below 100?

Lowering Your Total and LDL Cholesterol Levels

Lose weight if you are overweight.
Exercise regularly.
Eat fewer high-fat foods, like butter, cheese, meat, and some vegetable fats (palm oil and cocoa butter).
Eat more high-fiber foods, like vegetables, fruits, grains, and whole-grain breads, cereals, and pasta.

When is the best time to take Zetia?

Official Answer. There is no best time to take Zetia, as it works exactly the same whether you take it in the morning, afternoon or evening. Zetia is taken once a day, at the same time each day and it can be taken with or without food.

How is Zetia different from other statins?

Zetia reduces blood cholesterol in a different way to statin medications. Zetia lowers cholesterol levels by decreasing the amount of cholesterol that is absorbed from the small intestine, so that there is less intestinal cholesterol delivered to the liver. Continue reading Is this better than a statin?

How does Zetia work to lower blood cholesterol?

Is ezetimibe better than a statin?

Is ezetimibe better than a statin? Whether Zetia is better or worse than a statin at reducing cholesterol depends on the individual patient. Zetia and statins reduce cholesterol each with their own different mode of action.

When should I take Zetia If I am taking other medications?

If you also take other cholesterol medication: Take Zetia 2 hours before or 4 hours after taking cholestyramine, colestipol, or colesevelam. Tell your doctor about all your other medicines, especially: