What is the difference between Cushing syndrome and Cushing disease?

What is the difference between Cushing syndrome and Cushing disease?

Cushing disease is a specific type of Cushing syndrome. It occurs when a pituitary tumor causes the body to make too much cortisol. Cushing disease is the most common form of endogenous (from the body) Cushing syndrome, and makes up about 70% of Cushing syndrome cases.

Can Cushing’s syndrome turn into Addison’s disease?

Addison’s disease can also occur following treatment of Cushing’s disease (hyperadrenocorticism), in which too much cortisol and aldosterone are produced.

What are the signs and symptoms of Cushing syndrome of Addison disease?

Other possible signs and symptoms of Cushing syndrome

• Severe fatigue.
• Muscle weakness.
• Depression, anxiety and irritability.
• Loss of emotional control.
• Cognitive difficulties.
• New or worsened high blood pressure.
• Headache.
• Infections.

How is Cushings diagnosed?

Diagnosis is based on your medical history, a physical exam, and lab tests. Your doctor may ask if you are taking glucocorticoids or have had injections and rule that out before ordering lab tests. Doctors may use urine, saliva, or blood tests to diagnose Cushing’s syndrome.

Does Cushing’s cause hyponatremia?

This disorder is more common in patients with Cushing’s disease after surgery (approximately 20% of patients undergoing surgery for Cushing’s disease will have postoperative hyponatremia).

Can Cushing’s be mistaken for PCOS?

Cushing’s syndrome is characterized by symptoms that are strikingly similar to PCOS, including weight gain, hirsutism, facial puffiness, increased urination, and changes in skin texture.

What can mimic Cushing’s syndrome?

These tests help your doctor diagnose Cushing syndrome, and they may help rule out other medical conditions, such as polycystic ovary syndrome — a hormone disorder in women with enlarged ovaries. Depression, eating disorders and alcoholism also can partially mimic Cushing syndrome.