What is Podowart used for?

What is Podowart used for?

Podowart S Paint 10 ml is a combination medicine used to treat warts. Warts are small, fleshy bumps on the skin or mucous membrane. It is a type of skin infection caused by Human papillomavirus (HPV). Warts are contagious; they can spread from person to person.

What class of drug is Podophyllotoxin?

Furthermore, podophyllotoxin is classified as an arytetralin lignan for its ability to bind and deactivate DNA. It and its derivates bind Topo II and prevent its ability to catalyze rejoining of DNA that has been broken for replication.

What is biological source of podophyllotoxin?

Podophyllotoxin is an aryltetralin-type lignan isolated from species of Podophyllum [1,2]. Two most common sources are the rhizomes of Podophyllum peltatum (American mayapple) and Sinopodophyllum hexandrum Royle (Barberry family) [1,3].

Is Podowart harmful?

Podowart Paint may cause application site reactions such as burning, irritation, itching, and redness. They are not usually serious and resolve with time. If you experience these side effects, you may need to apply smaller amounts or use it less often. If they bother you or do not go away, tell your doctor.

How can I remove warts?

Nonprescription wart removal products such as salicylic acid are available as a patch, ointment, pad and liquid. For common warts, look for a 17 percent salicylic acid solution. These products (Compound W, Dr. Scholl’s Clear Away Wart Remover, others) are usually used daily, often for a few weeks.

Is podophyllotoxin poisonous?

Podophyllotoxin, a lignin, is the main toxic ingredient of Dysosma pleiantha (Bajiaolian) rhizome. Bajiaolian is the fifth highest cause of poisoning among herbal medicine in Taiwan (Karuppaiya and Tsay, 2015). Since the therapeutic and toxic doses are very close, Bajiaolian poisoning is frequently reported.

Where is podophyllotoxin found?

Podophyllotoxin (4) can be found in the rhizome and roots of Podophyllum hexandrum (P. emodi) or P. peltatum (Berberidaceae).

What is biological source of Cinchona?

The biological source of cinchona is the dried bark of the stem or root of it. • Commonly it is known as Peruvian or jesuit’s bark. • It belongs to the rubiaceae family.

Is Podofilox an antibiotic?

Podofilox is a topical agent used for the treatment of external genital warts and perianal warts. A lignan found in podophyllin resin from the roots of podophyllum plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic.

Is podophyllotoxin effective?

Podophyllotoxin 0.5% solution was the second most effective therapy, with a complete clearance probability of 92.6% (95% CrI 81.8% to 98.4%). Most other treatments improved the likelihood of complete clearance when compared with inactive placebo or no treatment with little difference in effectiveness between them.

Can I use Podowart daily?

Apply to the affected area(s) of the skin and leave on the skin for one to six hours. You may need to repeat the treatment every week for up to 6 weeks. Podowart Paint is used to remove skin warts.